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Toon Boom Animate
Easily create digital animations....
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Adobe Edge Animate
Tool for creating animated, interactive content using HTML, JavaScript and CSS....
Express Animate Animation Free for Mac
Create motion animations and add animations to your videos for free....
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NIH Image
NIH Image is a public domain image processing and analysis program for the Macintosh...
GroBoto
Create complex, dynamic, lyrical forms and animation....
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Synfig
Free and open source Film quality 2D vector animation...
ReplicantBody
Open source character animation toolkit developed in C++...
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Flip Boom Classic
Flip Boom Classic is a fun and creative tool designed to animate freely...
Drawing Board
Drawing Board - Free tool for kids, to let them do sketch-based animations easily...
Animation-Ish
Animation-Ish - Easy to use Mac application, designed to have your drawings up and moving in minutes...
Mimic Pro
Mimic Pro - Create and edit facial animation sequences...
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Facilis Engine
Facilis Engine - Up and coming graphics engine written entirely in managed code...